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Independent variable Dependent variable Condition(s) Test(s)
None Continuous One variable One-sample T-confidence interval
Two variables  

  • Parametric requirementsa
  • Nonparametric requirementsb
Correlation  

Spearman p

None Discrete One variable Chi-square goodness of fit
Two variables Chi-square test of independence
Two variables, very small data sets Fisher exact test
Discrete Continuous Independent variable (two levels)c
Unpaired, parametric requirementsa  

Unpaired, nonparametric requirementsb

Paired, parametric requirementsa

Paired, nonparametric requirementsb

Two-sample t test  

Mann-Whitney U

Paired t test

Wilcoxon matched-pair test

Independent variable (two or more levels)c
Unpaired, parametric requirementsa  

Unpaired, nonparametric requirementsb

Paired, parametric requirementsa

One-way analysis of variance  

Kruskal-Wallis

Complete randomized block

More than one independent variablea n-way analysis of variance
Discrete Discrete Two variables
Unpaired  

Unpaired, very small data sets

Paired

Chi-square test of independence  

Fisher exact test

McNemar test

Risk estimates
Retrospective  

Prospective

Odds ratio  

Relative risk ratio

Continuous Continuous Two variablesa Linear regression
More than one independent variable Multiple regression

aParametric elements are those in which a population is normally distributed and the variances are approximately equal.
b Nonparametric requirements are those that do not require the data to be equally distributed and are appropriate for ordinal dependent variables.
cLevels refer to the number of possibilities in a discrete variable (e.g., three treatment options for the independent variable would indicate three treatment levels).

Table borrowed from: DeMuth JE. Overview of biostatistics used in clinical research. AJHP. 2008; 66:70-81.


Flow chart for selecting commonly used statistical tests

Click here for a detailed description.


Flow chart borrowed from: http://abacus.bates.edu/~ganderso/biology/resources/statistics.html